How To Install probalign on Ubuntu 22.04

In this tutorial we learn how to install probalign on Ubuntu 22.04. probalign is multiple sequence alignment using partition function posterior probabilities

Introduction

In this tutorial we learn how to install probalign on Ubuntu 22.04.

What is probalign

probalign is:

Probalign uses partition function posterior probability estimates to compute maximum expected accuracy multiple sequence alignments. It performs statistically significantly better than the leading alignment programs Probcons v1.1, MAFFT v5.851, and MUSCLE v3.6 on BAliBASE 3.0, HOMSTRAD, and OXBENCH benchmarks. Probalign improvements are largest on datasets containing N/C terminal extensions and on datasets with long and heterogeneous length sequences. On heteregeneous length datasets containing repeats Probalign alignment accuracy is 10% and 15% higher than the other three methods when standard deviation of length is at least 300 and 400.

There are three methods to install probalign on Ubuntu 22.04. We can use apt-get, apt and aptitude. In the following sections we will describe each method. You can choose one of them.

Install probalign Using apt-get

Update apt database with apt-get using the following command.

sudo apt-get update

After updating apt database, We can install probalign using apt-get by running the following command:

sudo apt-get -y install probalign

Install probalign Using apt

Update apt database with apt using the following command.

sudo apt update

After updating apt database, We can install probalign using apt by running the following command:

sudo apt -y install probalign

Install probalign Using aptitude

If you want to follow this method, you might need to install aptitude first since aptitude is usually not installed by default on Ubuntu. Update apt database with aptitude using the following command.

sudo aptitude update

After updating apt database, We can install probalign using aptitude by running the following command:

sudo aptitude -y install probalign

How To Uninstall probalign on Ubuntu 22.04

To uninstall only the probalign package we can use the following command:

sudo apt-get remove probalign

Uninstall probalign And Its Dependencies

To uninstall probalign and its dependencies that are no longer needed by Ubuntu 22.04, we can use the command below:

sudo apt-get -y autoremove probalign

Remove probalign Configurations and Data

To remove probalign configuration and data from Ubuntu 22.04 we can use the following command:

sudo apt-get -y purge probalign

Remove probalign configuration, data, and all of its dependencies

We can use the following command to remove probalign configurations, data and all of its dependencies, we can use the following command:

sudo apt-get -y autoremove --purge probalign

References

Summary

In this tutorial we learn how to install probalign package on Ubuntu 22.04 using different package management tools: apt, apt-get and aptitude.