How To Install chimeraslayer on Ubuntu 22.04

In this tutorial we learn how to install chimeraslayer on Ubuntu 22.04. chimeraslayer is detects likely chimeras in PCR amplified DNA

Introduction

In this tutorial we learn how to install chimeraslayer on Ubuntu 22.04.

What is chimeraslayer

chimeraslayer is:

ChimeraSlayer is a chimeric sequence detection utility, compatible with near-full length Sanger sequences and shorter 454-FLX sequences (~500bp).

Chimera Slayer involves the following series of steps that operate to flag chimeric 16S rRNA sequences:

  1. the ends of a query sequence are searched against an included database of reference chimera-free 16S sequences to identify potential parents of a chimera
  2. candidate parents of a chimera are selected as those that form a branched best scoring alignment to the NAST-formatted query sequence
  3. the NAST alignment of the query sequence is improved in a ‘chimera-aware’ profile-based NAST realignment to the selected reference parent sequences
  4. an evolutionary framework is used to flag query sequences found to exhibit greater sequence homology to an in silico chimera formed between any two of the selected reference parent sequences.

To run Chimera Slayer, you need NAST-formatted sequences generated by the nast-ier utility.

ChimeraSlayer is part of the microbiomeutil suite.

There are three methods to install chimeraslayer on Ubuntu 22.04. We can use apt-get, apt and aptitude. In the following sections we will describe each method. You can choose one of them.

Install chimeraslayer Using apt-get

Update apt database with apt-get using the following command.

sudo apt-get update

After updating apt database, We can install chimeraslayer using apt-get by running the following command:

sudo apt-get -y install chimeraslayer

Install chimeraslayer Using apt

Update apt database with apt using the following command.

sudo apt update

After updating apt database, We can install chimeraslayer using apt by running the following command:

sudo apt -y install chimeraslayer

Install chimeraslayer Using aptitude

If you want to follow this method, you might need to install aptitude first since aptitude is usually not installed by default on Ubuntu. Update apt database with aptitude using the following command.

sudo aptitude update

After updating apt database, We can install chimeraslayer using aptitude by running the following command:

sudo aptitude -y install chimeraslayer

How To Uninstall chimeraslayer on Ubuntu 22.04

To uninstall only the chimeraslayer package we can use the following command:

sudo apt-get remove chimeraslayer

Uninstall chimeraslayer And Its Dependencies

To uninstall chimeraslayer and its dependencies that are no longer needed by Ubuntu 22.04, we can use the command below:

sudo apt-get -y autoremove chimeraslayer

Remove chimeraslayer Configurations and Data

To remove chimeraslayer configuration and data from Ubuntu 22.04 we can use the following command:

sudo apt-get -y purge chimeraslayer

Remove chimeraslayer configuration, data, and all of its dependencies

We can use the following command to remove chimeraslayer configurations, data and all of its dependencies, we can use the following command:

sudo apt-get -y autoremove --purge chimeraslayer

References

Summary

In this tutorial we learn how to install chimeraslayer package on Ubuntu 22.04 using different package management tools: apt, apt-get and aptitude.