How To Install profbval on Ubuntu 22.04

In this tutorial we learn how to install profbval on Ubuntu 22.04. profbval is predictor of flexible/rigid protein residues from sequence

Introduction

In this tutorial we learn how to install profbval on Ubuntu 22.04.

What is profbval

profbval is:

PROFbval can be useful for both protein structure and function predictions. For instance, a biologist can locate potentially antigenic determinants by identifying the most flexible residues on the protein surface. Additionally, a crystallographer can locate residues that potentially have high experimental B-values.

PROFbval takes the following input, further described on profbval(1):

  • a protein sequence in a FASTA file
  • secondary structure and solvent accessibility prediction by prof(1)
  • an HSSP file

Background: the mobility of a given residue on the protein surface is related to its functional role. Therefore, identification of extremely rigid or flexible residues on the protein surface is helpful for identifying functionally important residues in proteins. A common measure of atom mobility in proteins is B-value data from x-ray crystallography structures. PROFbval is the first tool to predict normalized backbone B-values from amino-acid sequence.

There are three methods to install profbval on Ubuntu 22.04. We can use apt-get, apt and aptitude. In the following sections we will describe each method. You can choose one of them.

Install profbval Using apt-get

Update apt database with apt-get using the following command.

sudo apt-get update

After updating apt database, We can install profbval using apt-get by running the following command:

sudo apt-get -y install profbval

Install profbval Using apt

Update apt database with apt using the following command.

sudo apt update

After updating apt database, We can install profbval using apt by running the following command:

sudo apt -y install profbval

Install profbval Using aptitude

If you want to follow this method, you might need to install aptitude first since aptitude is usually not installed by default on Ubuntu. Update apt database with aptitude using the following command.

sudo aptitude update

After updating apt database, We can install profbval using aptitude by running the following command:

sudo aptitude -y install profbval

How To Uninstall profbval on Ubuntu 22.04

To uninstall only the profbval package we can use the following command:

sudo apt-get remove profbval

Uninstall profbval And Its Dependencies

To uninstall profbval and its dependencies that are no longer needed by Ubuntu 22.04, we can use the command below:

sudo apt-get -y autoremove profbval

Remove profbval Configurations and Data

To remove profbval configuration and data from Ubuntu 22.04 we can use the following command:

sudo apt-get -y purge profbval

Remove profbval configuration, data, and all of its dependencies

We can use the following command to remove profbval configurations, data and all of its dependencies, we can use the following command:

sudo apt-get -y autoremove --purge profbval

References

Summary

In this tutorial we learn how to install profbval package on Ubuntu 22.04 using different package management tools: apt, apt-get and aptitude.