How To Install sim4db on Debian 10
Introduction
In this tutorial we learn how to install sim4db on Debian 10.
What is sim4db
sim4db is:
Sim4db performs fast batch alignment of large cDNA (EST, mRNA) sequence sets to a set of eukaryotic genomic regions. It uses the sim4 and sim4cc algorithms to determine the alignments, but incorporates a fast sequence indexing and retrieval mechanism, implemented in the sister package ’leaff’, to speedily process large volumes of sequences.
While sim4db produces alignments in the same way as sim4 or sim4cc, it has additional features to make it more amenable for use with whole-genome annotation pipelines. A script file can be used to group pairings between cDNAs and their corresponding genomic regions, to be aligned as one run and using the same set of parameters. Sim4db also optionally reports more than one alignment for the same cDNA within a genomic region, as long as they meet user-defined criteria such as minimum length, percentage sequence identity or coverage. This feature is instrumental in finding all alignments of a gene family at one locus. Lastly, the output is presented either as custom sim4db alignments or as GFF3 gene features.
This package is part of the Kmer suite.
There are three methods to install sim4db on Debian 10. We can use apt-get, apt and aptitude. In the following sections we will describe each method. You can choose one of them.
Install sim4db Using apt-get
Update apt database with apt-get using the following command.
sudo apt-get update
After updating apt database, We can install sim4db using apt-get by running the following command:
sudo apt-get -y install sim4db
Install sim4db Using apt
Update apt database with apt using the following command.
sudo apt update
After updating apt database, We can install sim4db using apt by running the following command:
sudo apt -y install sim4db
Install sim4db Using aptitude
If you want to follow this method, you might need to install aptitude first since aptitude is usually not installed by default on Debian. Update apt database with aptitude using the following command.
sudo aptitude update
After updating apt database, We can install sim4db using aptitude by running the following command:
sudo aptitude -y install sim4db
How To Uninstall sim4db on Debian 10
To uninstall only the sim4db package we can use the following command:
sudo apt-get remove sim4db
Uninstall sim4db And Its Dependencies
To uninstall sim4db and its dependencies that are no longer needed by Debian 10, we can use the command below:
sudo apt-get -y autoremove sim4db
Remove sim4db Configurations and Data
To remove sim4db configuration and data from Debian 10 we can use the following command:
sudo apt-get -y purge sim4db
Remove sim4db configuration, data, and all of its dependencies
We can use the following command to remove sim4db configurations, data and all of its dependencies, we can use the following command:
sudo apt-get -y autoremove --purge sim4db
Dependencies
sim4db have the following dependencies:
References
Summary
In this tutorial we learn how to install sim4db package on Debian 10 using different package management tools: apt, apt-get and aptitude.
