How To Install sift on Ubuntu 18.04

In this tutorial we learn how to install sift on Ubuntu 18.04. sift is predicts if a substitution in a protein has a phenotypic effect

Introduction

In this tutorial we learn how to install sift on Ubuntu 18.04.

What is sift

sift is:

SIFT is a sequence homology-based tool that sorts intolerant from tolerant amino acid substitutions and predicts whether an amino acid substitution in a protein will have a phenotypic effect. SIFT is based on the premise that protein evolution is correlated with protein function. Positions important for function should be conserved in an alignment of the protein family, whereas unimportant positions should appear diverse in an alignment.

There are three methods to install sift on Ubuntu 18.04. We can use apt-get, apt and aptitude. In the following sections we will describe each method. You can choose one of them.

Install sift Using apt-get

Update apt database with apt-get using the following command.

sudo apt-get update

After updating apt database, We can install sift using apt-get by running the following command:

sudo apt-get -y install sift

Install sift Using apt

Update apt database with apt using the following command.

sudo apt update

After updating apt database, We can install sift using apt by running the following command:

sudo apt -y install sift

Install sift Using aptitude

If you want to follow this method, you might need to install aptitude first since aptitude is usually not installed by default on Ubuntu. Update apt database with aptitude using the following command.

sudo aptitude update

After updating apt database, We can install sift using aptitude by running the following command:

sudo aptitude -y install sift

How To Uninstall sift on Ubuntu 18.04

To uninstall only the sift package we can use the following command:

sudo apt-get remove sift

Uninstall sift And Its Dependencies

To uninstall sift and its dependencies that are no longer needed by Ubuntu 18.04, we can use the command below:

sudo apt-get -y autoremove sift

Remove sift Configurations and Data

To remove sift configuration and data from Ubuntu 18.04 we can use the following command:

sudo apt-get -y purge sift

Remove sift configuration, data, and all of its dependencies

We can use the following command to remove sift configurations, data and all of its dependencies, we can use the following command:

sudo apt-get -y autoremove --purge sift

References

Summary

In this tutorial we learn how to install sift package on Ubuntu 18.04 using different package management tools: apt, apt-get and aptitude.