How To Install last-align on Debian 12

Learn how to install last-align on Debian 12 with this tutorial. last-align is genome-scale comparison of biological sequences

Introduction

In this tutorial we learn how to install last-align on Debian 12.

What is last-align

last-align is:

LAST is software for comparing and aligning sequences, typically DNA or protein sequences. LAST is similar to BLAST, but it copes better with very large amounts of sequence data. Here are two things LAST is good at:

  • Comparing large (e.g. mammalian) genomes.
  • Mapping lots of sequence tags onto a genome.

The main technical innovation is that LAST finds initial matches based on their multiplicity, instead of using a fixed size (e.g. BLAST uses 10-mers). This allows one to map tags to genomes without repeat-masking, without becoming overwhelmed by repetitive hits. To find these variable-sized matches, it uses a suffix array (inspired by Vmatch). To achieve high sensitivity, it uses a discontiguous suffix array, analogous to spaced seeds.

There are three methods to install last-align on Debian 12. We can use apt-get, apt and aptitude. In the following sections we will describe each method. You can choose one of them.

Install last-align Using apt-get

Update apt database with apt-get using the following command.

sudo apt-get update

After updating apt database, We can install last-align using apt-get by running the following command:

sudo apt-get -y install last-align

Install last-align Using apt

Update apt database with apt using the following command.

sudo apt update

After updating apt database, We can install last-align using apt by running the following command:

sudo apt -y install last-align

Install last-align Using aptitude

If you want to follow this method, you might need to install aptitude first since aptitude is usually not installed by default on Debian. Update apt database with aptitude using the following command.

sudo aptitude update

After updating apt database, We can install last-align using aptitude by running the following command:

sudo aptitude -y install last-align

How To Uninstall last-align on Debian 12

To uninstall only the last-align package we can use the following command:

sudo apt-get remove last-align

Uninstall last-align And Its Dependencies

To uninstall last-align and its dependencies that are no longer needed by Debian 12, we can use the command below:

sudo apt-get -y autoremove last-align

Remove last-align Configurations and Data

To remove last-align configuration and data from Debian 12 we can use the following command:

sudo apt-get -y purge last-align

Remove last-align configuration, data, and all of its dependencies

We can use the following command to remove last-align configurations, data and all of its dependencies, we can use the following command:

sudo apt-get -y autoremove --purge last-align

Dependencies

last-align have the following dependencies:

References

Summary

In this tutorial we learn how to install last-align package on Debian 12 using different package management tools: apt, apt-get and aptitude.