How To Install bwa on Fedora 34

bwa is Burrows-Wheeler Alignment tool

Introduction

In this tutorial we learn how to install bwa on Fedora 34.

What is bwa

BWA is a program for aligning sequencing reads against a large reference genome (e.g. human genome). It has two major components, one for read shorter than 150bp and the other for longer reads.

We can use yum or dnf to install bwa on Fedora 34. In this tutorial we discuss both methods but you only need to choose one of method to install bwa.

Install bwa on Fedora 34 Using dnf

Update yum database with dnf using the following command.

sudo dnf makecache --refresh

The output should look something like this:

Fedora 34 - x86_64                               20 kB/s | 6.6 kB     00:00
Fedora 34 openh264 (From Cisco) - x86_64        1.4 kB/s | 989  B     00:00
Fedora Modular 34 - x86_64                       68 kB/s | 6.5 kB     00:00
Fedora 34 - x86_64 - Updates                    3.5 kB/s | 6.2 kB     00:01
Fedora Modular 34 - x86_64 - Updates             17 kB/s | 5.9 kB     00:00
Metadata cache created.

After updating yum database, We can install bwa using dnf by running the following command:

sudo dnf -y install bwa

Install bwa on Fedora 34 Using yum

Update yum database with yum using the following command.

sudo yum makecache --refresh

The output should look something like this:

Fedora 34 - x86_64                               20 kB/s | 6.6 kB     00:00
Fedora 34 openh264 (From Cisco) - x86_64        1.4 kB/s | 989  B     00:00
Fedora Modular 34 - x86_64                       68 kB/s | 6.5 kB     00:00
Fedora 34 - x86_64 - Updates                    3.5 kB/s | 6.2 kB     00:01
Fedora Modular 34 - x86_64 - Updates             17 kB/s | 5.9 kB     00:00
Metadata cache created.

After updating yum database, We can install bwa using yum by running the following command:

sudo yum -y install bwa

How To Uninstall bwa on Fedora 34

To uninstall only the bwa package we can use the following command:

sudo dnf remove bwa

bwa Package Contents on Fedora 34

/usr/bin/bwa
/usr/bin/qualfa2fq.pl
/usr/bin/xa2multi.pl
/usr/lib/.build-id
/usr/lib/.build-id/d3
/usr/lib/.build-id/d3/fa0842a777382907e58e06b344ddb2992f7ed6
/usr/share/bwa/bwakit
/usr/share/bwa/bwakit/README.md
/usr/share/bwa/bwakit/bwa-postalt.js
/usr/share/bwa/bwakit/run-HLA
/usr/share/bwa/bwakit/run-bwamem
/usr/share/bwa/bwakit/run-gen-ref
/usr/share/bwa/bwakit/typeHLA-selctg.js
/usr/share/bwa/bwakit/typeHLA.js
/usr/share/bwa/bwakit/typeHLA.sh
/usr/share/doc/bwa
/usr/share/doc/bwa/COPYING
/usr/share/doc/bwa/NEWS.md
/usr/share/doc/bwa/README-alt.md
/usr/share/doc/bwa/README.md
/usr/share/man/man1/bwa.1.gz

References

Summary

In this tutorial we learn how to install bwa on Fedora 34 using yum and dnf.