How To Install bowtie2 on CentOS 8

bowtie2 is An ultra fast and memory-efficient read aligner

Introduction

In this tutorial we learn how to install bowtie2 on CentOS 8.

What is bowtie2

Bowtie 2 is an ultra fast and memory-efficient tool for aligning sequencing reads to long reference sequences. It is particularly good at aligning reads of about 50 up to 100s or 1,000s of characters, and particularly good at aligning to relatively long (e.g. mammalian) genomes. Bowtie 2 indexes the genome with an FM Index to keep its memory footprint small genome, its memory footprint is typically around 3.2 GB. Bowtie 2 supports gapped, local, and paired-end alignment modes.

We can use yum or dnf to install bowtie2 on CentOS 8. In this tutorial we discuss both methods but you only need to choose one of method to install bowtie2.

Install bowtie2 on CentOS 8 Using dnf

Update yum database with dnf using the following command.

sudo dnf makecache --refresh

The output should look something like this:

CentOS Linux 8 - AppStream                                       43 kB/s | 4.3 kB     00:00    
CentOS Linux 8 - BaseOS                                          65 kB/s | 3.9 kB     00:00    
CentOS Linux 8 - ContinuousRelease                               43 kB/s | 3.0 kB     00:00    
CentOS Linux 8 - Extras                                          23 kB/s | 1.5 kB     00:00    
CentOS Linux 8 - FastTrack                                       40 kB/s | 3.0 kB     00:00    
CentOS Linux 8 - HighAvailability                                36 kB/s | 3.9 kB     00:00    
CentOS Linux 8 - Plus                                            24 kB/s | 1.5 kB     00:00    
CentOS Linux 8 - PowerTools                                      50 kB/s | 4.3 kB     00:00    
Extra Packages for Enterprise Linux Modular 8 - x86_64           13 kB/s | 9.2 kB     00:00    
Extra Packages for Enterprise Linux 8 - x86_64                   24 kB/s | 8.5 kB     00:00    
Metadata cache created.

After updating yum database, We can install bowtie2 using dnf by running the following command:

sudo dnf -y install bowtie2

Install bowtie2 on CentOS 8 Using yum

Update yum database with yum using the following command.

sudo yum makecache --refresh

The output should look something like this:

CentOS Linux 8 - AppStream                                       43 kB/s | 4.3 kB     00:00    
CentOS Linux 8 - BaseOS                                          65 kB/s | 3.9 kB     00:00    
CentOS Linux 8 - ContinuousRelease                               43 kB/s | 3.0 kB     00:00    
CentOS Linux 8 - Extras                                          23 kB/s | 1.5 kB     00:00    
CentOS Linux 8 - FastTrack                                       40 kB/s | 3.0 kB     00:00    
CentOS Linux 8 - HighAvailability                                36 kB/s | 3.9 kB     00:00    
CentOS Linux 8 - Plus                                            24 kB/s | 1.5 kB     00:00    
CentOS Linux 8 - PowerTools                                      50 kB/s | 4.3 kB     00:00    
Extra Packages for Enterprise Linux Modular 8 - x86_64           13 kB/s | 9.2 kB     00:00    
Extra Packages for Enterprise Linux 8 - x86_64                   24 kB/s | 8.5 kB     00:00    
Metadata cache created.

After updating yum database, We can install bowtie2 using yum by running the following command:

sudo yum -y install bowtie2

How To Uninstall bowtie2 on CentOS 8

To uninstall only the bowtie2 package we can use the following command:

sudo dnf remove bowtie2

bowtie2 Package Contents on CentOS 8

/usr/bin/bowtie2
/usr/bin/bowtie2-align-l
/usr/bin/bowtie2-align-s
/usr/bin/bowtie2-build
/usr/bin/bowtie2-build-l
/usr/bin/bowtie2-build-s
/usr/bin/bowtie2-inspect
/usr/bin/bowtie2-inspect-l
/usr/bin/bowtie2-inspect-s
/usr/lib/.build-id
/usr/lib/.build-id/18
/usr/lib/.build-id/18/bad035629a4ca1daf523aa269fd3d958e09aa0
/usr/lib/.build-id/79
/usr/lib/.build-id/79/98d757ca706b4da4a1f060536c3eed2caeb5e8
/usr/lib/.build-id/91
/usr/lib/.build-id/91/6fae9a8def67662263cd7316804a1135ed297b
/usr/lib/.build-id/9a
/usr/lib/.build-id/9a/cefd8e81b5568a79b338cd647311284ce05f56
/usr/lib/.build-id/b0
/usr/lib/.build-id/b0/0d6d174c4107f7fe2faf4bfa542745ac698c1f
/usr/lib/.build-id/d8
/usr/lib/.build-id/d8/686fd7823e43a5c4f0692f8a6e8a74a4e7a04f
/usr/share/doc/bowtie2
/usr/share/doc/bowtie2/AUTHORS
/usr/share/doc/bowtie2/MANUAL
/usr/share/doc/bowtie2/MANUAL.markdown
/usr/share/doc/bowtie2/NEWS
/usr/share/doc/bowtie2/TUTORIAL
/usr/share/licenses/bowtie2
/usr/share/licenses/bowtie2/LICENSE
/usr/share/man/man1/bowtie2-build.1.gz
/usr/share/man/man1/bowtie2-inspect.1.gz
/usr/share/man/man1/bowtie2.1.gz

References

Summary

In this tutorial we learn how to install bowtie2 on CentOS 8 using yum and dnf.